T he malaria parasite has a complex, multistage life cycle occurring within two living beings, the vector mosquitoes and the vertebrate hosts. The survival and development of the parasite within the invertebrate and vertebrate hosts, in intracellular and extracellular environments, is made possible by a toolkit of more than 5, genes and their specialized proteins that help the parasite to invade and grow within multiple cell types and to evade host immune responses. The surface proteins and metabolic pathways keep changing during these different stages, that help the parasite to evade the immune clearance, while also creating problems for the development of drugs and vaccines. Life Cycle of Malaria Parasite [ Source ].
There are many orphanages in the state that work towards develop character and instill confidence Every modern technology in the banking sector raises a new security threat. Malayalis have experienced intemperate language hurled at them from street-side stages for a long time. But it has not been that long since it has started engulfing them.